That being said, I came across a study done in the last 12 months on the ‘base’ solutions in e-juice, specifically PG, VG, and PEG. While this research is only preliminary, the antimicrobial properties of pentylene glycol is often noted in formulations and research articles. Best Skin Whitening Lightening Creams 2020, What Are The Benefits of Pentylene Glycol, Difference Between Humectant, Emollient, Occlusive, Everything You Need to Know About Peptides. E-Cigarettes: Myth Vs. PE and PEG MAY be harmless in SOME but not all. Propylene glycol and glycerin often appear the same since they are colourless, odourless, sweet and syrupy. So, in short, PG is not only harmless, it also induces a state of increased healthiness. Ok… now lets break down all of the chemical compounds that big tobacco puts into cigarettes. Pentane diol vs. pentylene glycol. References: Johnson, W et al. ‘Margin of safety of pentylene glycol using measurements of cutaneous absorption and volatility’, Regulatory Toxicology and Pharmacology, vol. TO LEARN MORE ABOUT THE DETAILS OF THESE RELATIONSHIPS AND HOW PRODUCTS ARE RANKED ON OUR SITE, PLEASE READ THE "FULL DISCLOSURE" AND "METHODOLOGY" SECTIONS. 106-111. Laboratory studies on the inhalation of vaporized/aerosolized PEG. Came here searching for info on PEG and of course google leads me to a page made by an asshole moron. Propylene glycol is also used to make polyester compounds and as a base for de-icing solutions. 50C1307PZG. If you have sensitive skin that is prone to irritation, consult your dermatologist about whether this ingredient is best for you. 147s-168s. Pentylene glycol. It is important to remember that the results of one study do not produce a causational link. THIS SITE IS FOR INFORMATIONAL PURPOSES ONLY AND SHOULD NOT BE USED AS A SUBSTITUTE FOR ADVICE OR TREATMENT FROM A QUALIFIED MEDICAL PROFESSIONAL. Propanediol vs. propylene glycol. Steiner, A, Kugarajan, K, Wullimann, M, Ruty, B. Since about 20-30% of teens and young adults have tried vaping, this may now be the main source of exposure to PG. This characteristic makes pentylene glycol a great ingredient to emulsify and thicken products. if (!window.AdButler){(function(){var s = document.createElement("script"); s.async = true; s.type = "text/javascript";s.src = 'http://ads.ecigmedia.com/app.js';var n = document.getElementsByTagName("script")[0]; n.parentNode.insertBefore(s, n);}());} 1,2-glycols are also used for their conditioning abilities for both the skin and hair. Pentylene glycol also has the added benefit of acting as a preservative, which minimizes the need to add other preservatives to formulations. Acetyl glucosamine is a skin-replenishing ingredient that helps to reduc... What Is Acetyl Hexapeptide 8? ‘1, 2- Alkanediols for Cosmetic Preservation’, Cosmetics and Toiletries. THE OWNER OF THEDERMREVIEW.COM HAS MATERIAL BUSINESS RELATIONSHIPS WITH ADVANCED DERMATOLOGY AND FORMULYST, WHOSE PRODUCTS WE ALSO REVIEW AND RANK. Hence the picture above. 0005343920 . Study: http://ntr.oxfordjournals.org/content/early/2014/05/14/ntr.ntu078.full It is not, in fact, used in any anti-freeze. What is propylene glycol? 106-111. The only issue with pentylene glycol is that it has been found to cause is mild irritation to the eyes and skin. Fireball Whiskey was recalled in some European countries in 2014 because levels of propylene glycol were above the level allowed in those counties. It can act as a solvent and stabilizer for many products containing oils. Dr. O’Keefe: “Food additives are regulated in the U.S. based on their function and in what food category they can be used. Results: http://ntr.oxfordjournals.org/content/early/2014/05/14/ntr.ntu078/T2.expansion.html Pentylene Glycol uses and safety in cosmetics assesed by Truth In Aging Free shipping on all domestic orders over $49 ... "It has properties that are similar to a known allergen--propylene glycol--although it is considered by some to be less irritating or allergenic." is the bacterial killing properties in PG, also in VG??? It is a hydrophilic ingredient, which means that it binds well to water. Side by Side Comparison – Dipropylene Glycol vs Propylene Glycol in Tabular Form 5. If you want to make sure that your ingredient is plant based and approved to be used in "natural" or "organic" formulations, make inquiries by your supplier. Go! Of course, they also did so in an effort to shut the ANTZ (Anti-Nicotine and Tobacco Zealots) up… a move which ultimately failed because they have abandoned all attention to scientific evidence in exchange for a vendetta against the industry as a whole. What is Dipropylene Glycol? Please feel free to spread this around to all the skeptics you know. Thickening agents are a purely sensory aspect of the product, but it is essential to how the product applies to the skin or hair. Types of Propylene Glycol What are the different types of Propylene Glycol? Conditioning and thickening  Again, it has to be in higher concentrations and be directly applied to your skin, but good news is that this simply isn’t the situation with our dryer cloths. Propylene Glycol vs. var abkw = window.abkw || ''; What Is Isohexadecane? At low temperatures, propylene glycol solutions become considerably more viscous than ethylene glycol solutions. Reality, A Comprehensive List, Scientific Evidence in Support of Electronic Cigarette Technology, http://ntr.oxfordjournals.org/content/early/2014/05/14/ntr.ntu078.full, http://ntr.oxfordjournals.org/content/early/2014/05/14/ntr.ntu078/T2.expansion.html, http://ntr.oxfordjournals.org/content/early/2014/05/14/ntr.ntu078/T1.expansion.html, Discovering Slim’s E-Juice E-Juice Flavors, Pineapple Grapefruit E-liquid by Juice Head Freeze Review. This research seems to suggest that pentylene glycol may have this property, which may explain its ability to work as a preservative. This is however, not always the case. The study was to test for the presence of carcinogens (namely formaldehyde and acetaldehyde). Propylene glycol is added to food products, cosmetics, and even de-icing agents, like antifreeze. The term glycol is used when there are two hydroxyl groups present in neighboring carbon atoms. It produces ethylene glycol when processed.”. I am a vaper myself and consider this technology one of the most effective means of tobacco cessation known to man. Who is it for? 91049-43-3. panel has deemed all the 1,2-glycols that are used in skincare formulations, safe for use. Ethylene Glycol . Even this post is pretty full of mis-information. Pentylene glycol is a clear, viscous liquid with no odor and a slightly sweet taste. PG is metabolised by the human body into chemicals that are naturally occurring in normal, human metabolic functions. –Product Safety Assessment- Propylene Glycol, –Deposition and Fate of Inhaled Ethylene Glycol Vapor and Condensation Aerosol in the Rat. Oh, and I took your advice. It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water. Propylene glycol is one of those chemicals. EXCLUDING INTELLECTUAL PROPERTY OWNED BY OTHERS, ALL SITE CONTENT IS COPYRIGHTED OR LICENSED FOR USE BY THE OWNER OF THIS SITE. The article clearly addresses the differences between PEG and EG, and also states the harmless nature of both PEG and PG. Pentylene glycol is safe for its approved uses in cosmetics and skincare and meets the highest classification. However, this reaction is rare. The. Not only that, but I fact check the sources’ sources as well. Why propylene glycol versus ethylene glycol for winterization? In glycols, the alcohol groups are attached to different carbons. Antimicrobial and Preservative According to Herrmann, ethylene glycol (an ingredient used in antifreeze) is considered to be toxic and harmful, while propylene glycol is not. At ChemWorld, we provide different grades of Propylene Glycol. No, this effect has only been seen in PG. ‘Margin of safety of pentylene glycol using measurements of cutaneous absorption and volatility’, Regulatory Toxicology and Pharmacology, vol. Compare/Contrast. Use in Textiles: The largest amounts of propylene glycol are used in the textile industry, where it is an intermediate in polyester fiber production. I bow to your superiority. PG is present in some antifreeze products, but is colored pink to make it readily recognizable as non-toxic. The Final Word on Propylene Glycol vs. Polyethylene Glycol, Product Safety Assessment- Propylene Glycol, Deposition and Fate of Inhaled Ethylene Glycol Vapor and Condensation Aerosol in the Rat. It occurs … Pentylene glycol is part of the 1,2-glycol family of ingredients. Pentylene glycol meets these safety requirements. All skin types except those that have an identified allergy to it. 1,2-Pentanediol. The Food and Drug Administration (FDA) has classified propylene glycol as an additive that is generally recognized as safe for use in food. It produces ethylene glycol when processed. Please go fuck yourself with this article. This characteristic makes pentylene glycol a great ingredient to emulsify and thicken products. It is a colorless liquid with a mild odor. It is used in things such as eye drops, laxatives, liquid capsules, oral liquids, ointment bases etc. What I was pointing out was that despite PEG NOT BEING DANGEROUS, the E-cig industry switched to PG just to placate the worry-warts out there. Systematic Names. PEG is never a part of the process. Both of them possess low vapor pressure, also they contain high boiling points and the ability to lower the freeze point of water. Synonyms : Synonyms for propylene glycol include. Ethylene glycol has two carbon atoms, and propylene glycol has three carbon atoms per molecule. InChI … Pentylene Glycol – the even more compatible “Green variant” Recently, there is an even more compatible version of pentylene glycol, based on by-products from manufacturing processes based on sugarcane residues and corn spindles. Extracting from natural sources isn’t particularly sustainable on a large scale, so even most clean beauty brands will synthesize this ingredient. 12 Skincare Ingredients You May Want to Avoid. There are 16 other 1,2-glycols, only four are used in skincare. To help you understand better and learn some background information, pros and cons, and differences we created this tutorial. 2, pp. It is also present in a number of supermarket antifreeze products. ‘Safety Assessment of 1, 2-Glycols as Used in Cosmetics’, International Journal of Toxicology, vol. All I ask is that you give ejuiceconnoisseur.com credit as author. When ingested (swallowed, not inhaled) PEG is metabolised first into glycolic acid, then into oxalic acid… which is dangerous. Ethylene glycol and propylene glycol are organic compounds with alcohol functional groups. Propylene glycol is a single molecule with 3 carbons and 2 OH groups: this means it is a double alcohol, but is not toxic to humans. Stearyl alcohol is a natural fatty alcohol that is used as an emollient, em... What Is Acetyl Glucosamine? CBD For Pets: Is It Good? Hence the picture above. Propylene glycol is an FDA-approved additive for military dietary rations (Agency for Toxic Substances and Disease Registry 1997). Glycerin is also called glycerol. Being a large organic alcohol, propylene glycol provides excellent moisturizing properties to the skin. & Kunze, G, 2017. The 1,2-glycols are characterized by the presence of two hydroxyl or alcohol groups on the first and second attachment points along the carbon chain. Steiner, A, Kugarajan, K, Wullimann, M, Ruty, B. Although they share some physical properties, they have very distinctive features and it is very important to identify these compounds accurately due to the toxicity of propylene glycol. Pentylene glycol does not have any evidence to suggest toxicity or carcinogenicity. EINECS 226-285-3. Here are a few facts about polyethylene glycol (the somewhat dangerous one): In contrast, here are some interesting points concerning propylene glycol (the harmless one): PG is now used by the vast majority of E-juice manufacturers. Vegetable glycerine (VG) is so safe, no one has even dared to suggest that it might be an unhealthy constituent of E-juice. Here is a breakdown of each one: Propylene Glycol - 99.9% Pure internally repackaged certified USP grade that is packaged in containers starting at 2 oz to 5 Gallons. Of the two, PG is slightly better, which is why most of the E-cigarette industry has switched from PEG to PG. Pillai, R, Schmaus, G, Pfeiffer, A, Lange, S & Trunet, A, 2013. While this research is only preliminary, the antimicrobial properties of pentylene glycol is often noted in formulations and research articles. Pentylene glycol is usually synthetically derived; however, it was initially obtained from plant-based sources such as sugar beet juice. –Two-week aerosol inhalation study on polyethylene glycol (PEG) 3350 in F-344 rats. The concern arises when propylene glycol is heated up and inhaled. THOSE RELATIONSHIPS MAY AFFECT HOW WE REVIEW AND RANK PRODUCTS OR SERVICES MENTIONED ON THE SITE. I keep reading warnings, many by the uneducated masses of parrots populating the green face of the Earth and some by the supposedly educated, medical professionals of the world, which impress upon those being warned that the liquid used in E-cigarettes is also used in antifreeze, making it extremely toxic to human beings… and animals, too, allegedly. Please google Propylene glycol and status epilepticus, Polyethylene glycol is, in fact, used in antifreeze because it lowers the freezing temperature of water. Keep an eye on: It can also be referred to by the names 1,2- dihydroxypentane, 1,2-pentanediol, and pentane-1,2-diol. Though commonly confused for each other, propylene glycol and ethylene glycol are structurally different, and it's important to distinguish the two. Your info is grossly misleading and wrong regarding PEG. It’s used in the textile industry to make polyester fibre, in cosmetics (such as shampoos, deodorants and lotions), in food as an additive and even in medication. Even the electronic cigarettes that DO utilize polyethylene glycol (PEG) come nowhere near this mark. What Are The Benefits of Pentylene Glycol? Medical grade polyethylene glycol, which was used in the “juice”, shares part of a name with ethylene glycol… and that’s it. What Are Parabens – And Are They Bad For You? OTHER COMPANIES’ MARKS USED ON THIS SITE REMAIN THE INTELLECTUAL PROPERTY OF THEIR RESPECTIVE OWNERS. Propanediol and Propylene Glycol have the same Empirical Formula (C3H8O2), the molecular structure of each compound is different. The other 12 are arachidyl glycol, cetyl glycol, hexacosyl glycol, lauryl glycol, myristyl glycol, octacosanyl glycol, stearyl glycol, decylene glycol, 1,2-butanediol, C14-18 glycol, C18-30 glycol, and C20-30 glycol. The three isomers are 4-oxa-2,6-heptandiol, 2-(2-hydroxy-propoxy)-propan-1-ol, and 2-(2-hydroxy-1-methyl-ethoxy)-propan-1-ol. Overview of Propylene Glycol (PG) vs. The different chemical and physical properties result in different toxicology profiles and separate International … http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135271/. Isohexadecane is an ingredient used in skincare and cosmetic formulations to... What is Stearyl Alcohol? Each hydroxyl group is separately attache… AdButler.ads.push({handler: function(opt){ AdButler.register(165395, 174783, [300,250], 'placement174783'+opt.place, opt); }, opt: { place: plc174783++, keywords: abkw, domain: 'ads.ecigmedia.com', click:'CLICK_MACRO_PLACEHOLDER' }}); © 2017 Ejuice Econnoisseur. Also, the study above mentions PEG 3500 for the substance used in the rat lab study. Please keep your facts straight. Turns out the Propylene Glycol did no measurable damage to my colon or lower intestinal tract. Propylene glycol is the main ingredient in e-liquids inhaled as ‘vapour’ along with nicotine in e-cigarettes (‘vaping’). PE and kidneys. In fact, although propylene glycol (or PG) is used in antifreeze as well, it’s only used in RV and Marine antifreeze, colored pink to designate it’s non-toxic qualities. Structure Descriptors. However, when considered the uses, both are used for somewhat same purposes. Its chemical formula is CH 3 CH(OH)CH 2 OH. The resulting chemicals are pyruvic and lactic acids, both of which are quite normal in our bodies. Caprylyl glycol (1,2-octanediol) is an alcohol derived from caprylic acid, an eight carbon saturated fatty acid found in the milk of some mammals, as well as palm and coconut oils. Propylene glycol contains 3 carbon atoms, while butylene glycol is a little larger and contains 4 carbon atoms. Propylene Glycol vs. Propanediol. the good:Pentylene glycol helps to stabilize and thicken products. var AdButler = AdButler || {}; AdButler.ads = AdButler.ads || []; EC 226-285-3. All glycols are a type of alcohol, and butylene and propylene glycol have a similar molecular shape. ‘1, 2- Alkanediols for Cosmetic Preservation’, Cosmetics and Toiletries. 87, pp. Other Registry Number. This danger is present in PEG, but as stated above, not enough to cause harm. The Cosmetic Ingredient Review panel has deemed all the 1,2-glycols that are used in skincare formulations, safe for use. They found that one of the main ingredients in E-liquid was polyethylene glycol, which is used in antifreeze and is fairly toxic to humans in large quantities. Everything You Need to Know about Hyaluronic Acid. Ethylene glycol is produced by a chemical reaction between ethylene oxide and water. 31, iss. Cosmetic Ingredient Review, 2011. In addition to being approved for human consumption by the FDA, PG is also approved for human.   Side Effects of Propylene Glycol . 31, iss. This antifreeze scare is nothing new. 147s-168s. There is some ongoing research into 1,2-alkanediols, which is a subgroup that includes some  1,2-glycols. The CIR Expert Panel has evaluated the safety of the 1,2-glycol, propylene glycol and polypropylene glycols and concluded that these ingredients are safe for use in cosmetic products at concentrations up to 50.0%. Stabilize and thicken products an eye on: it can cause minor irritation to the eyes and skin a. 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